Updated September 10, 2026: An earlier version of this review recommended 1906 Midnight Drops for sleep, described Chill and Midnight as containing corydalis, and listed alpha-GPC and GABA in formulas that no longer carry them. Following the ProPublica and Denver Gazette reporting on liver-injury cases tied to Midnight Drops, we removed the Midnight recommendation, split the lineup into the brand's dispensary and online channels using its current ingredient panels, and added the Colorado exit, the settlement, and the Massachusetts bulletin. Our full report on the Midnight Drops cases.
The brand
1906 is named after the year before the US government began restricting cannabis. The brand makes small tablets it calls "Drops" that pair a low cannabinoid dose with botanical ingredients aimed at a specific outcome: focus, energy, relaxation, sleep, or, in one case, arousal. The pitch is closer to the supplement aisle than the candy aisle, and that is deliberate. 1906 wants to be in your medicine cabinet, not your snack drawer. The catch, as Colorado found out, is that a supplement-style product carries supplement-style risks, and nobody in the cannabis testing chain was checking the supplement half.
What happened with 1906 Midnight Drops?
Colorado's health department received its first reports of liver injury tied to Midnight Drops in March 2022. State regulators posted an informational notification that July, Massachusetts issued a precautionary bulletin in August, and Colorado posted a second notice in June 2023, when the manufacturer halted production. By May 2024 the state had 52 harm reports. The brand left Colorado in early 2024 and settled with the state in 2025.
The ingredient under investigation was never the THC. Midnight contained corydalis, a root extract whose active compound, tetrahydropalmatine, Colorado's July 22, 2022 notice tied to possible liver injury. That notice also relayed Sima Sciences' assertion that drops made on or after March 1, 2022 contained no corydalis. The company reformulated with Stephania, which regulators later concluded carries a compound with the same chemical makeup. On August 12, 2022 the Massachusetts Cannabis Control Commission opened its own investigation into marijuana products containing Corydalis yanhusuo and issued a precautionary bulletin on the compound, without ordering a recall.
The Colorado exit came in two steps. In January 2024 the brand told Westword it was leaving the Colorado market on its own and would fill orders through February. On September 19, 2025, Sima Sciences, its affiliates, and co-founder Peter Barsoom settled with the Colorado attorney general: $400,000 in fines, an agreement to cease Colorado operations, and a further $600,000 if the terms are breached. The attorney general's release gives no end date; ProPublica reports the bar runs until at least 2027. The companies denied violating consumer protection law, and the brand's own statement on Midnight Drops is still posted on its dispensary site. We covered the full timeline, the regulator's delays, and one patient's case. At its peak, 1906 made 81 percent of the pills sold in Colorado dispensaries. The brand that took the medicine-cabinet positioning most seriously was the one whose herbal ingredient put people in a gastroenterologist's office.
What does 1906 sell now?
Two lines, and the difference matters. The dispensary line, sold through state-licensed retail, lists Sleep, Genius, Bliss, Love, Chill, Go, Boost 5mg, RSO 5mg, and Boost+ 30mg. The online line at 1906.shop is hemp-derived: the same product names at 2mg of delta-9 THC per tablet, plus Pain AM and Pain PM gummies at 10mg. Neither line lists corydalis or Stephania on any panel we checked.
Genius, dispensary line (2.5mg THC, 2.5mg CBD, 2.5mg CBG per drop): The focus product. A serving is two drops, fifteen servings to a tin, and each serving carries 250mg rhodiola, 200mg bacopa, 200mg galangal, 80mg L-theanine, 75mg theobromine, and a 40mg coffee blend. No alpha-GPC, which an earlier version of this page listed. The caffeine and L-theanine pairing is the part with real evidence behind it, and it still earns our focus pick. The online Genius runs 2mg THC with lighter botanicals and 20mg of caffeine.
Go, dispensary line (5mg THC, 5mg CBD per drop, 20 per tin): The energy product: 120mg L-theanine, 100mg theobromine, 80mg caffeine, and 75mg galangal per drop. No GABA, despite what our older ranking copy said. The caffeine is doing the work here. The THC is along for the ride. The online Go is the same botanical stack at 2mg THC.
Sleep, dispensary line (5mg THC, 5mg CBD, 2mg CBN): The product that replaced Midnight, and the most telling item in the catalog. No botanical at all: three cannabinoids and a tablet coating. After the corydalis and Stephania episode, the sleep formula is the one place 1906 stopped adding plants. The product image on the brand's own site is still named MIDNIGHT.png, which is either an oversight or the most honest thing on the page. At 2mg CBN it sits well below the 20mg the Bonn-Miller 2024 trial used for sleep maintenance, so treat it as a light onset aid, not a maintenance product. The online Sleep drops to 2mg THC.
Chill, Bliss, and Love: Both lines carry all three. We have verified the online panels only. Online Chill (2mg THC, 25mg CBD, 5mg CBG) lists 50mg L-theanine and 7.5mg magnolia bark extract, the one traditional-medicine extract left in the catalog, and no corydalis. Online Bliss pairs theobromine with 20mg sceletium tortuosum, a South African herb sold as a mood lifter. Online Love stacks theobromine, ashwagandha, muira puama, catuaba, and damiana. The dispensary panels for these three are not published in a form we have checked, so we do not describe them.
Boost 5mg, RSO 5mg, Boost+ 30mg (dispensary only) and Pain AM / Pain PM (online only): Boost is THC with no botanical, the cleanest microdose vehicle in the line precisely because nothing else is in it. Boost+ at 30mg is the only product 1906 makes for people with a tolerance. The online Pain gummies stack 10mg THC with CBD, CBG, and CBC (AM) or CBDV, CBN, and CBC (PM) plus 40mg of boswellia resin.
Where can you buy 1906?
The dispensary line sells in East Coast and Midwest states, the description the brand gave Westword when it left Colorado in January 2024; the brand publishes no state list, so we do not name states beyond that. Not in Colorado, on either line: the voluntary exit came in January 2024 and the settlement in September 2025. The online line ships to 40 states and D.C., and its shipping policy says the rest in four words: "No sales to Colorado."
The online shipping list, from the brand's FAQ: Alabama, Arizona, Arkansas, California, Delaware, Florida, Georgia, Hawaii, Iowa, Illinois, Indiana, Kansas, Kentucky, Louisiana, Maine, Maryland, Michigan, Minnesota, Mississippi, Missouri, Nebraska, Nevada, New Hampshire, New Jersey, New Mexico, North Carolina, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Carolina, South Dakota, Tennessee, Texas, Virginia, West Virginia, Wisconsin, Wyoming, and D.C. One caveat the FAQ does not mention: that entire mail-order line runs on the federal hemp definition, and Section 781 caps hemp products at 0.4mg of total THC per container. A 2mg tablet in a 20-count tin is 40mg per container, a hundred times over the line. The online line loses federal hemp status on December 11, 2026 under the federal hemp ban. The dispensary line is untouched by it.
What 1906 does well
Speed and precision. The tablet format dissolves and activates faster than any gummy, with most users reporting effects inside 20 minutes. The doses are exact, the cannabinoid ratios are printed, and the brand publishes lab results. For someone who wants a repeatable low dose without chewing candy, the format is the best in the category, and the dispensary Boost at 5mg with nothing else in it is the cleanest version of that idea on the market.
Where 1906 falls short
The botanical stack is the brand's whole identity and its whole problem. Cannabis testing rules cover potency and contaminants. They do not evaluate rhodiola, bacopa, sceletium, muira puama, or magnolia, and they did not evaluate corydalis. The current labels are cleaner than the 2022 labels, but the model has not changed: a cannabis license plus a supplement formula, with no regulator responsible for the supplement half. There is also no flavor experience. You swallow a tablet. And the online line, at 2mg per Drop and $44 a tin, asks anyone with an established tolerance to take three or four to notice the THC.
Is 1906 worth buying?
For a clean, fast, low-dose THC tablet from a dispensary, yes: Boost and Genius are good at what they do, and Genius holds our focus pick on the strength of its caffeine and L-theanine pairing. For sleep, no. The current Sleep formula is underdosed for maintenance and the brand's record on sleep products is the reason this page has a correction note. For the online line, buy with the calendar in mind, because December 11 ends it. And for anything with an unfamiliar plant on the label, read the ingredient panel first and look up the plant second. That is the habit Midnight Drops should have taught every dispensary shopper, and it applies to 1906's current catalog as much as the old one.
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